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Schematically, the esophagus, lower esophageal sphincter (LES), and stomach can be envisioned as a simple plumbing circuit as described by Stein and coworkers. The esophagus functions as an antegrade pump, the LES as a v Visit Gastroesophageal Reflux Disease: Practice Essentials, Background, Anat (https://emedicine.medscape.com/article/176595-overview)
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