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Cytochrome P450 3A4 (abbreviated CYP3A4), is an important enzyme in the body, mainly found in the liver and in the intestine. Its purpose is to oxidize small foreign organic molecules (xenobiotics), such as toxins or drugs, so that they can be removed from the body. -- Wikipedia
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Diltiazem is a calcium channel blocker used to treat high blood pressure, angina, and certain heart rhythm problems.
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